Women Section
Biological Sciences

Ramanathan Sowdhamini
Education: Obtained her Masters degree in General Chemistry from the Indian Institute of Technology, Madras. Obtained Ph.D in Molecular Biophysics from Indian Institute of Science, Bangalore where she developed a method for modelling disulphide bridges in proteins with a view to introducing more covalent crosslinks in a protein to enhance its thermal stability. In 1992, she joined Professor Sir Tom Blundell's laboratory for her postdoctoral tenure, initially at Birkbeck College, London and later at the University of Cambridge( funded by Imperial Cancer Research Fund) She worked on fold recognition, comparison of protein folds, clustering of proteins into superfamilies and in the recognition of protein structural domains. She established a biocomputing laboratory in 1998 at the National Centre for Biological Sciences in Bangalore. Presently working as Associate Professor at National Centre for Biological Sciences (TIFR), Bangalore

Fields of Specialization:Her current area of research is in structure and function comparison of protein domain superfamilies that can be of value in predicting the functions of sequences available in genome databases. She has compiled databases of structurally aligned proteins grouped into superfamilies which permits identification of potential members in whole genome searches, analysis of the distribution of specific folds and families and for cross-genome comparisons.

Awarded National Award for Women Bioscientists under the young category for the year 2006 is conferred for her significant contribution for the development of sensitive tools for accurate structure and function of proteins. She has also received the International Senior Research Fellowship of the Wellcome Trust, UK. Dr. Sowdhamini has published original papers and review articles in national and international journals. She is an honorary fellow of Birkbeck College, London
Source: PIB Press Release
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