Date of Birth?: March 14,1943
Education: M. Sc., Ph. D., Professor, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, India
Fields of Specialization:Significant contributions in the biology of eukaryotic cells and their metabolism. Her work on the characterization of a novel rat cell surface hyaluronic acid binding protein, that has a human homologue implicated in cell signaling and tumor formation, is a major contribution in the development of early diagnostic markers for the detection of breast cancer.
Awarded: The Basanti Devi Amir Chand Prize 2004,( the earliest instituted award of ICMR,) for the significant research contributions made by scientists in the field of biomedical sciences .She has been awarded for ?Identification of HABP1 : A novel cell surface protein and its functions?. Prof. Datta?s research work has established the physiological significance of this protein since it expresses differentially on transformed cells, promotes cell adhesion and regulates tumour formation and sperm function. Prof. Datta?s group successfully identified the human homologue of this gene, named it HABP1,confirmed its localization on human chromosome 17p13.3 and placed this novel
gene on the map of human genome project from India. Prof. Datta?s continued effort using different approaches confirmed the multifunctionality of this gene. She established its role in cellular signalling and the oligomeric behaviour of this protein with special reference to its functional implications. A specific expression profile of this gene during tumour initiation, progression and metastasis as well as the inhibitory effect and induction of apoptosis has also been exhibited, suggesting the possible role of HABP1 as a cell cycle regulatory protein.
Prof. Kasturi Datta has more than 85 publications in reputed international and national scientific journals. She is a recipient of many awards including Ranbaxy Award for Basic Medical Sciences, Prof.M.R.N.Prasad Memorial and Dr.Darshan Ranganathan Memorial Lecture Awards (INSA) and Senior Women Bioscientist Award (DBT).
The Third World Academy of Sciences elected Prof. Datta as their Fellow in 2002, in Biochemistry and Biophysics. She is a Fellow of all the Science Academies of India.